Ep. 102: Comorbidities of Type 2 Inflammation - Connecting the Dots Between Multiple Allergic Conditions
Part of the series: Allergy, Asthma & Immunology Innovations Podcast
This podcast was made in partnership with Allergy & Asthma Network.
We thank Sanofi for sponsoring this episode. While they support the show, all opinions are our own, and sponsorship doesn’t influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.
LISTEN TO EPISODE 102:
Why do conditions like asthma, nasal polyps, or eczema become more severe when they coexist?
Kortney and Dr. Payel Gupta are joined by Dr. Michael Blaiss to explore the common thread linking multiple allergic and inflammatory diseases: Type 2 Inflammation. If you’ve ever wondered why certain conditions often appear together, this deep dive will help you connect the dots.
Type 2 Inflammation is a hot topic in immunology because it’s the engine that drives many allergic and inflammatory diseases. It’s also the key to modern treatment strategies, including targeted biologic therapies. Dr. Blaiss explains how clinicians recognize multiple Type 2-driven conditions in the same patient, why it is important to know the connection between multiple conditions and Type 2 inflammation, and the big-picture benefits of treating inflammation aggressively to prevent complications.
What We Cover in our Episode about The Diseases Related to Type 2 Inflammation:
Conditions Related to Type 2 Inflammation: Explore how nasal polyps (CRSwNP), rhinitis, asthma, atopic dermatitis (eczema), prurigo nodularis, eosinophilic esophagitis (EoE), and food allergies can all share a common inflammatory pathway.
The Likelihood of Having Multiple Type 2 Conditions: How often do patients have more than one condition related to Type 2 Inflammation, and why is recognizing overlap a potential game-changer for diagnosis and treatment?
Treating the Root Inflammation vs. Individual Symptoms: Discover how clinicians decide whether to address each condition separately or tackle the underlying Type 2 inflammatory process affecting them all.
Markers & Personalized Medicine: Dr. Blaiss discusses whether potential tests, such as eosinophil counts or IgE levels, can confirm Type 2 inflammation. He also explains how knowing you have Type 2 Inflammation can help guide targeted therapy.
Prevention & Aggressive Intervention: Understand why it’s crucial to treat inflammation early to reduce the risk of developing multiple Type 2 conditions and how this proactive approach benefits long-term health.
Listen now! Spotify • Amazon Music • Apple Podcast
About our Expert: Dr. Blaiss
Michael S. Blaiss, MD, FAAAAI, FACAAI has devoted his career to understanding and treating allergic diseases. He’s led pediatric allergy training programs, served as president of the American College of Allergy, Asthma & Immunology, and contributed to boards and societies aimed at advancing the care of allergic and immunologic conditions. His work focuses on bridging the gap between research and patient-centered treatment strategies—especially for those dealing with multiple Type 2 inflammatory conditions.
More resources about Type 2 Inflammation:
Type 2 Inflammation Overview – Explains the role of Type 2 inflammation in conditions like asthma and nasal polyps.
Type 2 Inflammation in Asthma – Details how Type 2 inflammation contributes to asthma and its symptoms.
Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) – Information on chronic rhinosinusitis, its diagnosis, and its prevalence.
Eosinophilic Esophagitis (EoE) – Overview of EoE, a condition caused by an increased number of eosinophils leading to inflammation in the esophagus.Nasal Polyps – Details on treatment options for nasal polyps, including the use of biologics like dupilumab.
Biologics: What They Are, How They Work, and Who Might Benefit – A webinar discussing biologic treatments for conditions associated with Type 2 inflammation.
Aspirin-Exacerbated Respiratory Disease (AERD) and the Role of Type 2 Inflammation – A webinar exploring the connection between AERD and Type 2 inflammation.
Timestamps
Our episode explores the connected conditions related to Type 2 Inflammation
01:07 Dr. Blaiss Introduction
02:32 What Conditions Are Related to Type 2 Inflammation
04:32 How Often Do Patients Have More Than One Type 2 Condition
05:47 Are Patients Treated with Multiple Conditions Differently
07:07 Why Type 2 Inflammation Means a More Severe Disease State
08:07 Do You Treat One Condition or All of Them at the Same Time?
10:27 Kortney Shares Her Treatment Path with Multiple Conditions
11:17 How Patients Realize Their Conditions Are Connected When Seeing Multiple Specialists
16:07 Is There a Marker That Can Tell If Someone Has Type 2 Inflammation?
19:27 Could AI Help Diagnose Type 2 Inflammation When Conditions Overlap?
20:41 What Can You Do to Prevent Getting More Type 2 Conditions?
22:36 Why Should You Aggressively Treat Inflammation?
